1. Introduction
Arctigenin is a phenolic dibenzylbutyrolactone lignan primarily derived from burdock seed (Arctium lappa), a well-known herb and nutraceutical widely used in traditional Asian medicine for its anti-inflammatory and antiviral properties. This compound exhibits strong anti-inflammatory effects by modulating key cytokines and inhibiting inducible nitric oxide synthase (iNOS). Due to its potent therapeutic potential, arctigenin is studied for its applications in managing acute inflammation and chronic diseases.
2. Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Arctigenin |
| Purity | 98% |
| Appearance | White Powder |
| CAS Number | 7770-78-7 |
| Molecular Weight | 372.41 |
| Molecular Formula | C21H24O6 |
| Melting Point | 98.0 to 102.0 °C |
| Solubility | Soluble in methanol, ethanol, DMSO, and other organic solvents |
3. Key Benefits & Functions
3.1 Anti-Inflammatory & Neuroprotective Properties
Arctigenin demonstrates powerful anti-inflammatory and antioxidant properties, supporting neuronal health. Research suggests it may protect dopamine neurons, making it valuable in managing Parkinson’s disease (PD) and other neurodegenerative conditions such as Alzheimer’s.
3.2 Potential Diabetes Support
Studies indicate that burdock-derived arctigenin may help regulate blood sugar levels, enhance glucose tolerance, and protect pancreatic cells—contributing to improved metabolic health.
3.3 Enhanced Athletic Performance & Fatigue Reduction
Arctigenin may reduce oxidative stress-induced muscle damage, increase endurance, and alleviate fatigue by lowering lactate and ammonia buildup. It also aids in post-exercise recovery, improving overall physical performance.
3.4 Antiviral & Anticancer Applications
In clinical settings, arctigenin has been investigated for its ability to inhibit tumor growth and metastasis, particularly in lung and colorectal cancers. It disrupts tumor cell metabolism by elevating ROS levels, making it a promising adjuvant in cancer therapy.
4. Applications
4.1 Anti-Inflammatory Therapy
Explore its role in developing novel treatments for inflammatory disorders.
4.2 Antiviral & Anticancer Formulations
Studied in combination with glucose analogues (e.g., 2-deoxyglucose) for synergistic antitumor effects.
4.3 Hemoprotective & Immunomodulatory Use
Helps counteract chemotherapy-induced leukopenia, supporting white blood cell regeneration.
5. Certificate of Analysis (COA)
| Test Parameter | Specification | Result |
|---|---|---|
| Purity | ≥98% | Complies |
| Loss on Drying | ≤5.0% | Complies |
| Heavy Metals | ≤10ppm | Complies |
| Microbial Limits | Within safe thresholds | Complies |
Why Choose Plant Extract Supply?
- High-Quality Standards: Our extracts are produced under strict GMP, HACCP, ISO, and FDA-compliant processes.
- Global Compliance: Products meet Kosher, Halal, and organic certification requirements.
- Safety Assurance: Third-party lab testing ensures premium quality and safety.
- Fast Shipping & Samples Available: Ready stock for immediate dispatch.
